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1

Optimized large-scale production of high titer lentivirus vector pseudotypes

Miguel Sena-Esteves, Jessica C. Tebbets, Sabine Steffens, Timothy Crombleholme, Alan W. Flake

Journal:

Journal of Virological Methods

Year:

2004

Language:

english

File:

PDF, 450 KB

english, 2004

2

Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects

Sandra Almeida, Zhijun Zhang, Giovanni Coppola, Wenjie Mao, Kensuke Futai, Anna Karydas, Michael D. Geschwind, M. Carmela Tartaglia, Fuying Gao, Davide Gianni, Miguel Sena-Esteves, Daniel H. Geschwind

Journal:

Year:

2012

Language:

english

File:

PDF, 2.27 MB

english, 2012

3

Titration of Lentivirus Vectors

Sena-Esteves, Miguel, Gao, Guangping

Journal:

Cold Spring Harbor Protocols

Year:

2018

Language:

english

File:

PDF, 246 KB

english, 2018

4

Production of Recombinant Adeno-Associated Viruses (rAAVs) by Transient Transfection

Su, Qin, Sena-Esteves, Miguel, Gao, Guangping

Journal:

Cold Spring Harbor Protocols

Year:

2020

Language:

english

File:

PDF, 249 KB

english, 2020

5

Evaluation of the role of the D2 dopamine receptor in myoclonus dystonia

Christine Klein, Nadia Gurvich, Miguel Sena-Esteves, Susan Bressman, Mitchell F. Brin, Barbara J. Ebersole, Stephen Fink, Lars Forsgren, Jennifer Friedman, David Grimes, Gosta Holmgren, Mårtin Kyllerm

Journal:

Annals of Neurology

Year:

2000

Language:

english

File:

PDF, 6.55 MB

english, 2000

6

Generation of stable retrovirus packaging cell lines after transduction with herpes simplex virus hybrid amplicon vectors

Miguel Sena-Esteves, Jürgen A. Hampl, Sara M. Camp, Xandra O. Breakefield

Journal:

The Journal of Gene Medicine

Year:

2002

Language:

english

File:

PDF, 272 KB

english, 2002

7

Transduction of satellite cells after prenatal intramuscular administration of lentiviral vectors

Tippi C. MacKenzie, Gary P. Kobinger, Jean-Pierre Louboutin, Antoneta Radu, Elizabeth H. Javazon, Miguel Sena-Esteves, James M. Wilson, Alan W. Flake

Journal:

The Journal of Gene Medicine

Year:

2005

Language:

english

File:

PDF, 622 KB

english, 2005

8

Transduction of human glial and neuronal tumor cells with different lentivirus vector pseudotypes

Sabine Steffens, Jessica Tebbets, Christof M. Kramm, Dirk Lindemann, Alan Flake, Miguel Sena-Esteves

Journal:

Journal of Neuro-Oncology

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

9

Directed evolution of adeno-associated virus for glioma cell transduction

Casey A. Maguire, Davide Gianni, Dimphna H. Meijer, Lev A. Shaket, Hiroaki Wakimoto, Samuel D. Rabkin, Guangping Gao, Miguel Sena-Esteves

Journal:

Journal of Neuro-Oncology

Year:

2010

Language:

english

File:

PDF, 363 KB

english, 2010

10

Spinal projections of the A5, A6 (locus coeruleus), and A7 noradrenergic cell groups in rats

Eveline Bruinstroop, Georgina Cano, Veronique G.J.M. Vanderhorst, Judney C. Cavalcante, Jena Wirth, Miguel Sena-Esteves, Clifford B. Saper

Journal:

The Journal of Comparative Neurology

Year:

2012

Language:

english

File:

PDF, 3.12 MB

english, 2012

11

Transduction of the inner mouse retina using AAVrh8 and AAVrh10 via intravitreal injection

Thomas J. Giove, Miguel Sena-Esteves, William D. Eldred

Journal:

Experimental Eye Research

Year:

2010

Language:

english

File:

PDF, 1.23 MB

english, 2010

12

RNAi blocks DYT1 mutant torsinA inclusions in neurons

Norman Kock, Andrew J. Allchorne, Miguel Sena-Esteves, Clifford J. Woolf, Xandra O. Breakefield

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 231 KB

english, 2006

13

Depletion of GGA3 Stabilizes BACE and Enhances β-Secretase Activity

Giuseppina Tesco, Young Ho Koh, Eugene L. Kang, Andrew N. Cameron, Shinjita Das, Miguel Sena-Esteves, Mikko Hiltunen, Shao-Hua Yang, Zhenyu Zhong, Yong Shen, James W. Simpkins, Rudolph E. Tanzi

Journal:

Year:

2007

Language:

english

File:

PDF, 1.56 MB

english, 2007

14

Healing Genes in the Nervous System

Xandra O. Breakefield, Miguel Sena-Esteves

Journal:

Year:

2010

Language:

english

File:

PDF, 316 KB

english, 2010

15

84. Adeno-associated virus gene therapy of feline gangliosidosis

Douglas Martin, M. Begona Cachon-Gonzalez, Miguel Sena-Esteves, Rena C. Baek, Thomas N. Seyfried, Timothy M. Cox, Nancy R. Cox

Journal:

Molecular Genetics and Metabolism

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

16

Gene transfer into the mammalian inner ear using HSV-1 and vaccinia virus vectors

Michael L Derby, Miguel Sena-Esteves, Xandra O Breakefield, David P Corey

Journal:

Hearing Research

Year:

1999

Language:

english

File:

PDF, 570 KB

english, 1999

17

Adeno-associated virus (AAV)[ndash ]mediated gene transfer in respiratory epithelium and submucosal gland cells in human fetal tracheal organ culture

Foong-Yen Lim, Bernard G. Martin, Miguel Sena-Esteves, Antoneta Radu, Timothy M. Crombleholme

Journal:

Journal of Pediatric Surgery

Year:

2002

Language:

english

File:

PDF, 208 KB

english, 2002

18

Regression of Schwannomas Induced by Adeno-Associated Virus-Mediated Delivery of Caspase-1

Prabhakar, Shilpa, Taherian, Mehran, Gianni, Davide, Conlon, Thomas J., Fulci, Giulia, Brockmann, Jillian, Stemmer-Rachamimov, Anat, Sena-Esteves, Miguel, Breakefield, Xandra O., Brenner, Gary J.

Journal:

Human Gene Therapy

Year:

2013

Language:

english

File:

PDF, 1.62 MB

english, 2013

19

Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects

Sandra Almeida, Zhijun Zhang, Giovanni Coppola, Wenjie Mao, Kensuke Futai, Anna Karydas, Michael D. Geschwind, M. Carmela Tartaglia, Fuying Gao, Davide Gianni, Miguel Sena-Esteves, Daniel H. Geschwind

Journal:

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

20

Microvesicle-associated AAV Vector as a Novel Gene Delivery System

Maguire, Casey A, Balaj, Leonora, Sivaraman, Sarada, Crommentuijn, Matheus HW, Ericsson, Maria, Mincheva-Nilsson, Lucia, Baranov, Vladimir, Gianni, Davide, Tannous, Bakhos A, Sena-Esteves, Miguel, Bre

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 2.08 MB

english, 2012

21

Quantification of nanosized extracellular membrane vesicles with scanning ion occlusion sensing

de Vrij, Jeroen, Maas, Sybren LN, van Nispen, Malisa, Sena-Esteves, Miguel, Limpens, Ronald WA, Koster, Abraham J, Leenstra, Sieger, Lamfers, Martine L, Broekman, Marike LD

Journal:

Year:

2013

Language:

english

File:

PDF, 4.65 MB

english, 2013

22

Hepatic production of transthyretin L12P leads to intracellular lysosomal aggregates in a new somatic transgenic mouse model

Batista, Ana Rita, Sena-Esteves, Miguel, Saraiva, Maria João

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 2.09 MB

english, 2013

23

Functional Coexpression of HSV-1 Thymidine Kinase and Green Fluorescent Protein: Implications for Noninvasive Imaging of Transgene Expression

Jacobs, Andreas, Dubrovin, Michael, Hewett, Jeff, Sena-Esteves, Miguel, Tan, Cui-Wen, Slack, Mark, Sadelain, Michele, Breakefield, Xandra O., Tjuvajev, Juri G.

Journal:

Year:

1999

Language:

english

File:

PDF, 520 KB

english, 1999

24

Gene therapy for the central nervous system in the lysosomal storage disorders

Kaye, Edward M, Sena-Esteves, Miguel

Journal:

Neurologic Clinics

Year:

2002

Language:

english

File:

PDF, 546 KB

english, 2002

25

Targeting Transforming Growth Factor α Expression to Discrete Loci of the Neuroendocrine Brain Induces Female Sexual Precocity

Florence Rage, Diane F. Hill, Miguel Sena-Esteves, Xandra O. Breakefield, Robert J. Coffey, Maria E. Costa, Samuel M. McCann and Sergio R. Ojeda

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.61 MB

english, 1997

26

Association of a Missense Change in the D2 Dopamine Receptor with Myoclonus Dystonia

Christine Klein, Mitchell F. Brin, Patricia Kramer, Miguel Sena-Esteves, Deborah de Leon, Dana Doheny, Susan Bressman, Stanley Fahn, Xandra O. Breakefield and Laurie J. Ozelius

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1018 KB

english, 1999

27

Gaussia Luciferase Variant for High-Throughput Functional Screening Applications

Maguire, Casey A., Deliolanis, Nikolaos C., Pike, Lisa, Niers, Johanna M., Tjon-Kon-Fat, Lee-Ann, Sena-Esteves, Miguel, Tannous, Bakhos A.

Journal:

Analytical Chemistry

Year:

2009

Language:

english

File:

PDF, 1.93 MB

english, 2009

28

Critical Issues in Gene Therapy for Neurologic Disease

Hsich, Gary, Sena-Esteves, Miguel, Breakefield, Xandra O.

Journal:

Human Gene Therapy

Year:

2002

Language:

english

File:

PDF, 1.09 MB

english, 2002

29

Gene Therapy for the Nervous System: Challenges and New Strategies

Maguire, Casey A., Ramirez, Servio H., Merkel, Steven F., Sena-Esteves, Miguel, Breakefield, Xandra O.

Journal:

Neurotherapeutics

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

30

Herpes Vector-Mediated Delivery of Marker Genes to Disseminated Central Nervous System Tumors

Kramm, Christof M., Rainov, Nikolai G., Sena-Esteves, Miguel, Chase, Maureen, Pechan, Peter A., Chiocca, E. Antonio, Breakefield, Xandra O.

Journal:

Human Gene Therapy

Year:

1996

Language:

english

File:

PDF, 10.15 MB

english, 1996

31

Correction of Acid beta -Galactosidase Deficiency in GM 1 Gangliosidosis Human Fibroblasts by Retrovirus VectorMediated Gene Transfer: Higher Efficiency of Release and Cross-Correction by the Murine Enzyme

Sena-Esteves, Miguel, Camp, Sara M., Alroy, Joseph, Breakefield, Xandra O.

Journal:

Human Gene Therapy

Year:

2000

Language:

english

File:

PDF, 428 KB

english, 2000

32

Long-Term Survival in a Rodent Model of Disseminated Brain Tumors by Combined Intrathecal Delivery of Herpes Vectors and Ganciclovir Treatment

Kramm, Christof M., Rainov, Nikolai G., Sena-Esteves, Miguel, Barnett, Faith H., Chase, Maureen, Herrlinger, Ulrich, Pechan, Peter A., Chiocca, E. Antonio, Breakefield, Xandra O.

Journal:

Human Gene Therapy

Year:

1996

Language:

english

File:

PDF, 2.43 MB

english, 1996

33

Evaluation and Optimization of the Administration of Recombinant Adeno-Associated Viral Vectors (Serotypes 2/1, 2/2, 2/rh8, 2/9, and 2/rh10) by Convection-Enhanced Delivery to the Striatum

White, Edward, Bienemann, Alison, Sena-Esteves, Miguel, Taylor, Hannah, Bunnun, Chotirote, Castrique, Emma, Gill, Steven

Journal:

Human Gene Therapy

Year:

2011

Language:

english

File:

PDF, 1.67 MB

english, 2011

34

Potentiated Gene Delivery to Tumors Using Herpes Simplex Virus/Epstein-Barr Virus/RV Tribrid Amplicon Vectors

Hampl, Jürgen A., Camp, Sara M., Mydlarz, Wojciech K., Hampl, Monika, Ichikawa, Tomotsuga, Chiocca, E. Antonio, Louis, David N., Sena-Esteves, Miguel, Breakefield, Xandra O.

Journal:

Human Gene Therapy

Year:

2003

Language:

english

File:

PDF, 2.69 MB

english, 2003

35

New Prodrug Activation Gene Therapy for Cancer Using Cytochrome P450 4B1 and 2-Aminoanthracene/4-Ipomeanol

Rainov, Nikolai G., Dobberstein, Karl-Ulrich, Sena-Esteves, Miguel, Herrlinger, Ulrich, Kramm, Christof M., Philpot, Richard M., Hilton, John, Chiocca, E. Antonio, Breakefield, Xandra O.

Journal:

Human Gene Therapy

Year:

1998

Language:

english

File:

PDF, 5.06 MB

english, 1998

36

889. Adeno-Associated Virus Gene Therapy of Feline Gangliosidosis

Martin, Douglas R., Cachon-Gonzalez, Begona, Sena-Esteves, Miguel, Hwang, Misako, Gentry, Atoska S., Morrison, Nancy E., Cox, Nancy R., Cox, Timothy M., Baker, Henry J.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

37

409. Complete Correction of Enzymatic Deficiency and Lysosomal Storage throughout the Brain in a Mouse Model of GM1-gangliosidosis after Neonatal Intracerebroventricular Injection of an AAV1 Vector Encoding Lysosomal Acid Beta- galactosidase

Broekman, Marike L. D., Baek, Rena, Comer, Laryssa A., Seyfried, Thomas N., Sena-Esteves, Miguel

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

38

438. Targeting HSV-1 Virions for Specific Binding to Epidermal Growth Factor Receptor-VIII on Tumor Cells

Grandi, Paola, Fernandez, Juliet, Szentirmai, Oscar, Carter, Robert, Breakefield, Xandra O., Sena-Esteves, Miguel

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

39

154. Tetracycline-Inducible HSV Amplicon Vectors with Expanded Range of Gene Expression Regulation

Comer, Laryssa A., Fernandez, Juliet L., Camp, Sara M., Tebbets, Jessica C., Breakefield, Xandra O., Sena-Esteves, Miguel

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

40

Triple Bioluminescence Imaging for In Vivo Monitoring of Cellular Processes

Maguire, Casey A, Bovenberg, M Sarah, Crommentuijn, Matheus HW, Niers, Johanna M, Kerami, Mariam, Teng, Jian, Sena-Esteves, Miguel, Badr, Christian E, Tannous, Bakhos A

Journal:

Molecular Therapy — Nucleic Acids

Year:

2013

Language:

english

File:

PDF, 1.50 MB

english, 2013

41

959. Tumor Therapy Via Vector-Regulated Expression of Mutant Sodium Channel

Tannous, Bakhos A., Perry, Katherine F., Sena-Esteves, Miguel, Garcias-Anoveros, Jaime, Jacobs, Andreas, Corey, David P., Weissleder, Ralph, Breakefield, Xandra O.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 122 KB

english, 2006

42

491. Mosaic AAV Vectors Display Novel Properties for Neuronal Transduction

LeRoy, Stanley G., Comer, Laryssa A., Costa, Fabricio F., Broekman, Marike L.D., Sena-Esteves, Miguel

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

43

Craniometaphyseal dysplasia and otolaryngology findings

Esteves, Sara Sena, Silva, Ana Pereira, Coutinho, Miguel Bebiano, Abrunhosa, José, Sousa, Cecília Almeida e

Journal:

International Journal of Pediatric Otorhinolaryngology Extra

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

44

Bis(monoacylglycero)phosphate: a secondary storage lipid in the gangliosidoses

Akgoc, Zeynep, Sena-Esteves, Miguel, Martin, Douglas R., Han, Xianlin, d’Azzo, Alessandra, Seyfried, Thomas N.

Journal:

The Journal of Lipid Research

Year:

2015

Language:

english

File:

PDF, 515 KB

english, 2015

45

Congenital defects of the middle ear - uncommon cause of pediatric hearing loss1,2

Esteves, Sara Duarte Sena, Silva, Ana Pereira da, Coutinho, Miguel Bebiano, Abrunhosa, José Manuel, Sousa, Cecília Almeida e

Journal:

Brazilian Journal of Otorhinolaryngology

Year:

2014

File:

PDF, 2.44 MB

2014

46

Systemic AAV9 gene transfer in adult GM1 gangliosidosis mice reduces lysosomal storage in CNS and extends lifespan

Weismann, Cara M., Ferreira, Jennifer, Keeler, Allison M., Su, Qin, Qui, Linghua, Shaffer, Scott A., Xu, Zuoshang, Gao, Guangping, Sena-Esteves, Miguel

Journal:

Human Molecular Genetics

Year:

2015

Language:

english

File:

PDF, 1.07 MB

english, 2015

47

Several rAAV Vectors Efficiently Cross the Blood–brain Barrier and Transduce Neurons and Astrocytes in the Neonatal Mouse Central Nervous System

Zhang, Hongwei, Yang, Bin, Mu, Xin, Ahmed, Seemin Seher, Su, Qin, He, Ran, Wang, Hongyan, Mueller, Christian, Sena-Esteves, Miguel, Brown, Robert, Xu, Zuoshang, Gao, Guangping

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 1.17 MB

english, 2011

48

Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model

Prabhakar, Shilpa, Zhang, Xuan, Goto, June, Han, Sangyeul, Lai, Charles, Bronson, Roderick, Sena-Esteves, Miguel, Ramesh, Vijaya, Stemmer-Rachamimov, Anat, Kwiatkowski, David J., Breakefield, Xandra O

Journal:

Neurobiology of Disease

Year:

2015

Language:

english

File:

PDF, 2.16 MB

english, 2015

49

Preventing Growth of Brain Tumors by Creating a Zone of Resistance

Maguire, Casey A, Meijer, Dimphna H, LeRoy, Stanley G, Tierney, Laryssa A, Broekman, Marike LD, Costa, Fabricio F, Breakefield, Xandra O, Stemmer-Rachamimov, Anat, Sena-Esteves, Miguel

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 549 KB

english, 2008

50

Mutant Sodium Channel for Tumor Therapy

Tannous, Bakhos A, Christensen, Adam P, Pike, Lisa, Wurdinger, Thomas, Perry, Katherine F, Saydam, Okay, Jacobs, Andreas H, García-Añoveros, Jaime, Weissleder, Ralph, Sena-Esteves, Miguel, Corey, Davi

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 4.26 MB

english, 2009

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